Moles can rarely transmit diseases to humans, but the parasites they carry are a greater cause for concern:
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Rabies
Moles can carry rabies, which is usually transmitted through the saliva of an infected animal. Moles are generally shy, but they may bite if they feel threatened, confused, or are handled.
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Ticks
Ticks that live on moles can carry diseases such as Lyme disease, Rocky Mountain spotted fever, anaplasmosis, and tularemia.
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Fleas
Fleas can carry parasitic organisms, like Bartonella and tapeworms, that can pass to pets and humans.
Moles can also cause other problems, such as:
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Damage to lawns: Moles can create unsightly holes and uneven surfaces that can be a tripping hazard.
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Damage to agricultural equipment: Molehills can damage equipment used to harvest silage.